Julien De Jonckheere

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Continuous Analgesia / Nociception balance evaluation during general anesthesia could be of precious help for the optimization of analgesic drugs delivery, limiting the risk of toxicity due to the use of opioid drugs, limiting the risk of post operative hyper algesia, and, probably, reducing time of recovery after surgical procedure. Heart Rate Variability(More)
Healthcare monitoring is a general concern for patients requiring a continuous medical assistance and treatment. In order to increase mobility of such patients, a huge effort is pursued worldwide for the development of wearable monitoring systems able to measure vital physiological parameters such as respiratory movements, cardiac activity, pulse oximetry,(More)
OBJECTIVES Systems controlling cardiovascular function are closely coupled with the perception of pain. Heart rate variability (HRV) is a well-established noninvasive measure of cardiac autonomic control. We hypothesized that pain may alter HRV in the newborn infant and that HRV analysis could be used as an indicator of prolonged pain in the newborn infant.(More)
The optimization of analgesic drugs delivery during general anesthesia requires to evaluate the pain/analgesia balance. Heart rate variability analysis has been shown in several studies to measure the autonomic nervous system tone, which is strongly influenced by anesthetic drugs. Recording RR series during general anesthesia enabled us to observe that the(More)
Healthcare monitoring applications requires the measurement and the analysis of multiple physiological data. In the field of biomedical research, these data are issued from different devices involving data centralization and synchronization difficulties. On the other hand, the analysis of the acquired data requires high level digital signal processing(More)
Heart Rate Variability analysis has been shown in several studies to measure the Autonomic Nervous System tone, which is strongly influenced by pain, stress or anxiety. We have previously described and developed an Analgesia/Nociception Index for pain measurement during surgical procedure. This index based on a heart rate variability analysis can be(More)
INTRODUCTION The analgesia nociception index (ANI) assesses the relative parasympathetic tone as a surrogate for antinociception/nociception balance in sedated patients. The aim of this study is to determine the effectiveness of ANI in detecting pain in deeply sedated critically ill patients. METHODS This prospective observational study was performed in(More)
The potential benefit of optical fiber sensors embedded into medical textiles for the continuous monitoring of patients for MRI is presented. We report a monitoring system based on the use of two novel non-intrusive optical sensing technologies designed to measure the elongation due to abdominal and thoracic motions during breathing. The developed system(More)
BACKGROUND Intubation is frequently performed in intensive care unit patients. Overinflation of the endotracheal tube cuff is a risk factor for tracheal ischemia and subsequent complications. Despite manual control of the cuff pressure, overinflation of the endotracheal cuff is common in intensive care unit patients. We hypothesized that efficient(More)
Prostate carcinoma has become the second most fatal cancer in American men. In rat Dunning prostate adenocarcinoma cells, increased cellular motility has been associated positively with their increased metastatic potential. However, the mechanism(s) responsible for regulation of tumor cell motility is poorly understood. We have reported that a lipoxygenase(More)