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STUDY DESIGN Multiple brace designs were simulated using a finite element model and their biomechanical effect was evaluated. OBJECTIVE To study correlations between immediate in-brace correction of coronal curves and bending moments acting on the apical vertebrae. SUMMARY OF BACKGROUND DATA Immediate in-brace correction has often been deemed as(More)
STUDY DESIGN Proof of concept of a spine surgery simulator (S3) for the assessment of scoliosis instrumentation configuration strategies. OBJECTIVE To develop and assess a surgeon-friendly spine surgery simulator that predicts the correction of a scoliotic spine as a function of the patient characteristics and instrumentation variables. SUMMARY OF(More)
The biomechanical influence of thoraco-lumbo-sacral bracing, a commonly employed treatment in scoliosis, is still not fully understood. The aim of this study was to compare the immediate corrections generated by different virtual braces using a patient-specific finite element model (FEM) and to analyze the most influential design factors. The 3D geometry of(More)
The distribution of stresses in the scoliotic spine is still not well known despite its biomechanical importance in the pathomechanisms and treatment of scoliosis. Gravitational forces are one of the sources of these stresses. Existing finite element models (FEMs), when considering gravity, applied these forces on a geometry acquired from radiographs while(More)
BACKGROUND A numerical based brace design platform, including biomechanical simulation, Computer Aided Design and Computer Aided Manufacturing (CAD/CAM) was developed to rationalize braces for the treatment of adolescent idiopathic scoliosis. The objective of this study was to test the feasibility of the approach and assess the effectiveness of braces(More)
Based on a three-dimensional patient-specific finite element model of the spine, rib cage, pelvis and abdomen, a parametric model of a thoraco-lumbo-sacral orthosis (TLSO) was built. Its geometry is custom-fit to the patient. The rigid shell, pads and openings are all represented. The interaction between the trunk and the brace is modeled by a(More)
simple, graphical test. Br Med J 1997; 315: 629–634. 13. Pfreundschuh M, Trumper L, Kloess M et al. Two-weekly or 3-weekly CHOP chemotherapy with or without etoposide for the treatment of elderly patients with aggressive lymphomas: results of the NHL-B2 trial of the DSHNHL. Blood 2004; 104: 634–641. 14. Osby E, Hagberg H, Kvaloy S et al. CHOP is superior to(More)
STUDY DESIGN A biomechanical study of the Charleston brace. OBJECTIVE To model the nighttime Charleston brace treatment and study its biomechanical action. SUMMARY OF BACKGROUND DATA The Charleston brace has been proposed as an alternative to the traditional daytime thoracolumbosacral orthosis for the treatment of moderate scoliotic deformities. It is(More)
STUDY DESIGN Feasibility study to compare the effectiveness of 2 brace design and fabrication methods for treatment of adolescent idiopathic scoliosis: a standard plaster-cast method and a computational method combining computer-aided design and fabrication and finite element simulation. OBJECTIVES To improve brace design using a new brace design method.(More)
with recurrent or metastatic squamous-cell carcinoma of the head and neck. Lancet Oncol 2009; 10: 247–257. 27. Reidy DL, Vakiani E, Fakih MG et al. Randomized, phase II study of the insulinlike growth factor receptor inhibitor IMC-A12, with or without cetuximab, in patients with cetuximabor panitumumab-refractory metastatic colorectal cancer. J Clin Oncol(More)