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STUDY DESIGN Proof of concept of a spine surgery simulator (S3) for the assessment of scoliosis instrumentation configuration strategies. OBJECTIVE To develop and assess a surgeon-friendly spine surgery simulator that predicts the correction of a scoliotic spine as a function of the patient characteristics and instrumentation variables. SUMMARY OF(More)
STUDY DESIGN Multiple brace designs were simulated using a finite element model and their biomechanical effect was evaluated. OBJECTIVE To study correlations between immediate in-brace correction of coronal curves and bending moments acting on the apical vertebrae. SUMMARY OF BACKGROUND DATA Immediate in-brace correction has often been deemed as(More)
STUDY DESIGN A biomechanical study of the Charleston brace. OBJECTIVE To model the nighttime Charleston brace treatment and study its biomechanical action. SUMMARY OF BACKGROUND DATA The Charleston brace has been proposed as an alternative to the traditional daytime thoracolumbosacral orthosis for the treatment of moderate scoliotic deformities. It is(More)
Based on a three-dimensional patient-specific finite element model of the spine, rib cage, pelvis and abdomen, a parametric model of a thoraco-lumbo-sacral orthosis (TLSO) was built. Its geometry is custom-fit to the patient. The rigid shell, pads and openings are all represented. The interaction between the trunk and the brace is modeled by a(More)
The biomechanical influence of thoraco-lumbo-sacral bracing, a commonly employed treatment in scoliosis, is still not fully understood. The aim of this study was to compare the immediate corrections generated by different virtual braces using a patient-specific finite element model (FEM) and to analyze the most influential design factors. The 3D geometry of(More)
The distribution of stresses in the scoliotic spine is still not well known despite its biomechanical importance in the pathomechanisms and treatment of scoliosis. Gravitational forces are one of the sources of these stresses. Existing finite element models (FEMs), when considering gravity, applied these forces on a geometry acquired from radiographs while(More)
BACKGROUND A numerical based brace design platform, including biomechanical simulation, Computer Aided Design and Computer Aided Manufacturing (CAD/CAM) was developed to rationalize braces for the treatment of adolescent idiopathic scoliosis. The objective of this study was to test the feasibility of the approach and assess the effectiveness of braces(More)
OBJECTIVE To study the biomechanical effectiveness of brace design parameters in right thoracic idiopathic scoliosis. METHODS A finite element model (FEM) of the spine, rib cage, pelvis and abdomen was adapted to the geometry of 8 patients with right-thoracic idiopathic scoliosis using a multi-view radiographic reconstruction technique. A detailed(More)
Karrison TG et al. Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck. Fakih MG et al. Randomized, phase II study of the insulin-like growth factor receptor inhibitor IMC-A12, with or without cetuximab, in patients with cetuximab-or panitumumab-refractory metastatic colorectal cancer. A et al. A(More)