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A dense map of genetic variation in the laboratory mouse genome will provide insights into the evolutionary history of the species and lead to an improved understanding of the relationship between inter-strain genotypic and phenotypic differences. Here we resequence the genomes of four wild-derived and eleven classical strains. We identify 8.27 million(More)
OBJECTIVE To evaluate the prevalence and severity of hyperprolactinemia among a large sample of patients with schizophrenia and related psychotic disorders treated with typical and atypical antipsychotic medications. METHOD Three electronic databases (general medical, psychiatric, and pharmacologic) containing the census data from November 2002 through(More)
OBJECTIVE--To study the association between diet and newly diagnosed NIDDM in the Wanigela people of Papua New Guinea, a population with an extraordinary susceptibility for NIDDM. RESEARCH DESIGN AND METHODS--We performed a case-control study of Wanigela people from an urban settlement (Koki). Case patients (n = 145) were asymptomatic subjects in whom NIDDM(More)
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INTRODUCTION Demand for flexible training is increasing. The contribution of such trainees to the trained medical workforce is not clear. METHODS All full time and flexible trainees in Scotland were 'tracked' at the completion of training. RESULTS 80% of flexible trainees took up a consultant post of which 93% were in Scotland. 82% of full time trainees(More)
The tomato fruit consists of a thick, fleshy pericarp composed predominantly of highly vacuolated parenchymatous cells, which surrounds the seeds. During ripening, the activation of gene expression results in dramatic biochemical and physiological changes in the pericarp. The polygalacturonase (PG) gene, unlike many fruit ripening-induced genes, is not(More)
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