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  • Nicolas Etique, Stéphane Flament, Julie Lecomte, Isabelle Grillier-Vuissoz
  • Biology, Medicine
  • International journal of oncology
  • 1 December 2007
  • Alcohol consumption is an increased risk factor for hormone-dependent breast cancer but the underlying molecular bases are unknown. Several studies suggest that ethanol could activate the estrogenContinue Reading
  • Julie Lecomte, Stéphane Flament, +4 authors Isabelle Grillier-Vuissoz
  • Biology, Medicine
  • Breast Cancer Research and Treatment
  • 1 December 2008
  • Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that can be activated by natural ligands such as 15-deoxy-delta(12,14)-prostaglandin J2 (15d-PGJ(2)) as well as syntheticContinue Reading
  • Christelle Colin, Stéphane Salamone, +5 authors Stéphane Flament
  • Biology, Medicine
  • Breast Cancer Research and Treatment
  • 1 November 2010
  • Numerous recent studies indicate that most anticancer effects of PPARγ agonists like thiazolidinediones are the result of PPARγ-independent pathways. These conclusions were obtained by severalContinue Reading