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In this paper we address the problem of nding the simulated system with the best (maximum or minimum) expected performance when the number of alternatives is nite, but large enough that ranking-and-selection procedures may require too much computation to be practical. Our approach is to use the data provided by the rst stage of sampling in a(More)
Recent incidents of avian flu (H5N1) in Asia and the pandemic influenza cases in history (1918, 1957 and 1968) suggest that a future pandemic influenza is inevitable and likely imminent. Governments and non-governmental organizations prepare response plans on how to react to a pandemic influenza. In this paper, we study the logistics side of the problem,(More)
The Internet is changing the automotive industry as the traditional manufacturer and dealer structure faces increased threats from third party e-tailers. Dynamic pricing together with the Direct-to-Customer business model can be used by manufacturers to respond to these challenges. Indeed, by coordinating production and inventory decisions with dynamic(More)
We study jointly determining prices and production in a multiple period horizon under a general , non-stationary stochastic demand function with a discrete menu of prices. We assume that the available production capacity is limited and unmet demand is lost. We incorporate discretionary sales, when inventory may be set aside to satisfy future demand even if(More)
Pandemic Flu „ " Epidemic over a wide geographic area and affecting a large proportion of the population. " Epidemiologists " There is a high chance that a Swine Flu „ Epidemiologists: " There is a high chance that a pandemic flu will hit the world in the near future " 2
To my parents, Ana and Cornel, for their unconditional and unbreakable support iii ACKNOWLEDGEMENTS I would like to thank my family, especially my husband, who has never stopped believing in me, and has never complained being a mother and a father to our two children while I was working on my research. Without him I would have never become the person I am(More)