Learn More
Learning-based models of anxiety disorders emphasize the role of aversive conditioning and retarded extinction in the etiology and maintenance of anxiety disorders. Yet few studies have examined these underlying processes in children, despite that some anxiety disorders typically onset during childhood. The authors examined the acquisition and extinction of(More)
OBJECTIVE To examine attentional bias towards angry and happy faces in 8-12 year old children with anxiety disorders (n=29) and non-anxious controls (n=24). METHOD Children completed a visual-probe task in which pairs of angry/neutral and happy/neutral faces were displayed for 500ms and were replaced by a visual probe in the spatial location of one of the(More)
The present study examined the magnitudes of startle blink reflexes and electrodermal responses in 4-8-year-old high anxious children (N=14) and non-anxious controls (N=11). Responses were elicited by 16 auditory startle trials during a baseline phase prior to an affective modulation phase involving 12 startle trials presented during angry and neutral(More)
PURPOSE To evaluate the efficacy, safety and tolerability of changing to travoprost BAK-free from prior prostaglandin therapy in patients with primary open-angle glaucoma or ocular hypertension. DESIGN Prospective, multi-center, historical control study. METHODS Patients treated with latanoprost or bimatoprost who needed alternative therapy due to(More)
BACKGROUND Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by a disturbed epidermal barrier. In a subset of patients, this is explained by nonsense mutations in the gene encoding filaggrin (FLG). OBJECTIVES We sought to evaluate the respective role of FLG mutations and proinflammatory cytokines and to assess the expression of(More)
The study of aversive Pavlovian conditioning in children can contribute to our understanding of how fears are acquired and extinguished during development. However, methodological issues hamper further research because of ethical and procedural concerns regarding the use of traditional aversive unconditional stimuli (USs) and no established method to(More)
Given the often reported relationships between sleep-wake regulation and the cerebral prostaglandins (PGs), the effect of chronic rapid eye movement (REM) sleep deprivation on brain PGE2 and PGD2 biosynthesis in mouse was evaluated, since they are known to have opposite actions as respectively wake- and sleep-inducing substances. Mice were subjected to 5(More)
The connections between the topics of responsibility, authority, and accountability (RAA) in aviation are discussed since a while. Nevertheless the currently proposed approaches are limited and do not allow to make a global assessment during the design of new operational ATM concepts that change the role of humans and technical systems. This paper suggests(More)
  • 1