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Modulation of remifentanil-induced postinfusion hyperalgesia by the β-blocker propranolol in humans.

• Larry F Chu, Tony Cun, +5 authors David J. Clark
• Pain
• 2012

Acute and chronic exposure to opioids has been associated with hyperalgesia in both animals and humans. A genetic analysis of opioid-induced hyperalgesia in mice linked the β(2)-adrenergic receptor… (More)

GRLD-1 regulates cell-wide abundance of glutamate receptor through post-transcriptional regulation

• George Jiaguo Wang, Lijun Kang, Julie Eunwoo Kim, Géraldine S. Maro, X. Z. Shawn Xu, Kang Shen
• Nature Neuroscience
• 2010

AMPA receptors mediate most of the fast postsynaptic response at glutamatergic synapses. The abundance of AMPA receptors in neurons and at postsynaptic membranes is tightly regulated. It has been… (More)

Tenofovir exposure alters associations of serum bicarbonate with chronic kidney disease risk in HIV-infected veterans.

• Julie Eunwoo Kim, Rebecca Scherzer, Michelle M. Estrella, Joachim H. Ix, Michael G. Shlipak
• AIDS
• 2016

OBJECTIVE Among HIV-infected persons, tenofovir disoproxil fumarate (TDF) use is associated with higher risk of developing chronic kidney disease (CKD). Because lower serum bicarbonate concentrations… (More)

Analgesic tolerance without demonstrable opioid-induced hyperalgesia: a double-blinded, randomized, placebo-controlled trial of sustained-release morphine for treatment of chronic nonradicular…

• Larry F Chu, Nicole D'arcy, +6 authors J. David Clark
• Pain
• 2012

Although often successful in acute settings, long-term use of opioid pain medications may be accompanied by waning levels of analgesic response not readily attributable to advancing underlying… (More)

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