Julie E Obbagy

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The Dietary Guidelines for Americans (DGA) are the cornerstone of US government efforts to promote health and prevent disease through diet and nutrition. The DGA currently provides guidelines for ages ≥ 2 y. In an effort to determine the strength of the evidence to support the inclusion of infants and children from birth to age 24 mo, the partner agencies(More)
Energy density is a relatively new concept that has been identified as an important factor in body weight control in adults and in children and adolescents. The Dietary Guidelines for Americans 2010 encourages consumption of an eating pattern low in energy density to manage body weight. This article describes the systematic evidence-based review conducted(More)
The murine bone marrow culture technique was used to prepare donor marrow for bone marrow transplantation across minor histocompatibility complex differences. Previous studies have shown that theta-positive cells are rapidly lost from such cultures and that transplantation of cultured marrow across major histocompatibility complex differences results in a(More)
There is substantial evidence for limited proliferative capacity of the hematopoietic progenitors. Hematopoiesis in mice is maintained by primitive stem cells that are assayed by their ability to form spleen colonies (CFU-S). To measure the average proliferative capacity of these cells (CFU-S). bone marrow containing 50-1 50 CFU-S is injected into lethally(More)
Bone marrow from old (greater than 2 yr of age) and young (8-10 wk of age) male C3H/HeJ mice was grown in long-term bone marrow cultures and assayed for weekly hematopoietic stem cell (CFUs) production and interval self-renewal capacity (R5). Greater numbers of CFUs were noted in old marrow as compared to young marrow cultures over the first 4 wk duration,(More)
Modifying the energy content of foods, particularly foods eaten away from home, is important in addressing the obesity epidemic. Chefs in the restaurant industry are uniquely placed to influence the provision of reduced-calorie foods, but little is known about their opinions on this issue. A survey was conducted among chefs attending US culinary meetings(More)
The use of the bone marrow culture technique was studied as a means to prepare donor marrow for bone marrow transplantation to avoid lethal graft-versus-host disease (GVHD). Preliminary experiments demonstrated the rapid loss of theta-positive cells in such cultures, so that theta-positive cells were not detected after 6 days. Initial experiments in C3H/HeJ(More)
The success of bone marrow transplantation depends not only on the engraftment of adequate numbers of hematopoietic stem cells but also on their self-renewal capacity, which must be sufficient to provide lifetime hematopoiesis. The lectin peanut agglutinin (PNA), when exposed to bone marrow, causes separation into two distinct fractions. The agglutinated(More)
t r s s s s t r The Dietary Guidelines for Americans (DGA) are jointly issued and updated every 5 years by the US Department of Agriculture (USDA) and the US Deartment of Health and Human Services (HHS). They rovide authoritative nutrition advice for people age 2 ears and older to promote health and reduce risk for ajor chronic diseases. To update the 2005(More)
Hypertension is a major risk factor for development of stroke, coronary heart disease, heart failure, and end-stage renal disease. In a systematic review of the evidence published from 2004 to 2009, the 2010 Dietary Guidelines Advisory Committee (DGAC) concluded there was moderate evidence of an inverse relationship between the intake of milk and milk(More)