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- Anamaria Necsulea, Magali Soumillon, +6 authors Henrik Kaessmann
- Nature
- 2014
Only a very small fraction of long noncoding RNAs (lncRNAs) are well characterized. The evolutionary history of lncRNAs can provide insights into their functionality, but the absence of lncRNA… (More)
In addition to the apical-basal polarity pathway operating in epithelial cells, a planar cell polarity (PCP) pathway establishes polarity within the plane of epithelial tissues and is conserved from… (More)
- Russell B. Fletcher, Julie C. Baker, Richard M Harland
- Development
- 2006
The relative contributions of different FGF ligands and spliceforms to mesodermal and neural patterning in Xenopus have not been determined, and alternative splicing, though common, is a relatively… (More)
- Bérénice A. Benayoun, Elizabeth A. Pollina, +14 authors A. GoÂmez Brunet
- Cell
- 2014
Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to mark the transcription start sites of active genes. Here, we show that H3K4me3 domains that spread more broadly… (More)
- Alayne L. Brunner, David S. Johnson, +12 authors Richard M. Myers
- Genome research
- 2009
To investigate the role of DNA methylation during human development, we developed Methyl-seq, a method that assays DNA methylation at more than 90,000 regions throughout the genome. Performing… (More)
- Edward B Chuong, Mohammed Azharul Karim Rumi, Michael J. Soares, Julie C. Baker
- Nature Genetics
- 2013
The mammalian placenta is remarkably distinct between species, suggesting a history of rapid evolutionary diversification. To gain insight into the molecular drivers of placental evolution, we… (More)
- Se-jin Yoon, Andrea Wills, Edward B Chuong, Rakhi Gupta, Julie C. Baker
- Genes & development
- 2011
Nodal signaling, mediated through SMAD transcription factors, is necessary for pluripotency maintenance and endoderm commitment. We identified a new motif, termed SMAD complex-associated (SCA), that… (More)
- Meng How Tan, Kin Fai Au, +5 authors Jin Billy Li
- Genome research
- 2013
The Xenopus embryo has provided key insights into fate specification, the cell cycle, and other fundamental developmental and cellular processes, yet a comprehensive understanding of its… (More)
- Nesanet Mitiku, Julie C. Baker
- Developmental cell
- 2007
We developed a comprehensive dataset that samples the mouse transcriptome every 6 hr, from gastrulation through organogenesis. We observe an abrupt increase in overall transcript diversity at the… (More)
- Kirstin Knox, Julie C. Baker
- Genome research
- 2008
The invention of the placenta facilitated the evolution of mammals. How the placenta evolved from the simple structure observed in birds and reptiles into the complex organ that sustains human life… (More)