Julie Brittenden

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BACKGROUND B-type natriuretic peptide (BNP) levels predict cardiovascular risk in several settings. We hypothesized that they would identify individuals at increased risk of early cardiac complications after major non-cardiac surgery. The current study tests this hypothesis. METHODS Two hundred and four patients undergoing major non-cardiac surgery were(More)
BACKGROUND Three daily portions of whole-grain foods could lower cardiovascular disease risk, but a comprehensive intervention trial was needed to confirm this recommendation. OBJECTIVES We aimed to assess the effects of consumption of 3 daily portions of whole-grain foods (provided as only wheat or a mixture of wheat and oats) on markers of(More)
Five cases of acute intestinal ischaemia due to occlusion of the superior mesenteric artery, all with a delay in diagnosis, are reported here. These cases illustrate the continuing difficulties, in clinical practice, in recognizing mesenteric ischaemia before intestinal infarction has occurred, despite the clinical awareness of this condition.
OBJECTIVE Platelet activation was assessed in patients with peripheral arterial disease compared with healthy control subjects. METHODS This prospective comparative study included 100 subjects: 40 consecutive patients with intermittent claudication, 20 consecutive patients with critical ischemia and tissue loss, and 40 healthy control subjects. Whole(More)
OBJECTIVE Omega-3 fatty acids have been shown to reduce platelet and endothelial activation in patients with or at risk of cardiac disease. We aimed to determine if Omega-3 fatty acid supplementation in addition to best medical therapy can reduce the increased platelet and endothelial activity that is present in patients with intermittent claudication. (More)
Colorectal cancer in patients under 45 years of age accounts for approximately 4% of all cases of colorectal cancer. The stage of disease at presentation is comparable with that of older patients. Histological evaluations of the cancers in the younger age group of patients reveal that approximately four times as many tumours are of the mucinous type and(More)
Penetrating atheromatous ulcers of the aorta are increasingly recognized as a distinct entity. Although their natural history remains ill-defined, such ulcers may lead to pseudoaneurysmal formation, dissection, rupture, or embolization. Given the morbidity associated with open repair, endovascular repair of penetrating atheromatous ulcers may be the(More)