Julie A. Zalikowski

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Systemic exposure to rosuvastatin in Asian subjects living in Japan or Singapore is approximately twice that observed in Caucasian subjects in Western countries or in Singapore. This study was conducted to determine whether pharmacokinetic differences exist among the most populous Asian subgroups and Caucasian subjects in the USA. Rosuvastatin(More)
2-(4-(4-(tert-Butylcarbamoyl)-2-(2-chloro-4-cyclopropylphenylsulfonamido)phenoxy)-5-chloro-2-fluorophenyl)acetic acid (AMG 853) is an orally bioavailable and potent dual antagonist of the D-prostanoid and chemoattractant receptor-homologous molecule expressed on T helper 2 cells receptors. The drug interaction potential of AMG 853, both as a victim and a(More)
curve; C max , peak drug concentration observed in plasma This article has not been copyedited and formatted. The final version may differ from this version. Abstract AMG 853 is an orally bioavailable and potent dual antagonist of the D-prostanoid (DP) and chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) receptors. The drug(More)
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