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Electrocardiographs recorded in a magnetic field for cardiac-gating in magnetic resonance imaging (MRI) are complicated by blood flow-induced potentials. This study examines which lead of the standard 12-lead ECG maximizes the QRS while minimizing flow-induced interference. Twelve-lead ECGs were performed on normal volunteers (n = 9) and patients (n = 13)(More)
In guinea pig ventricular myocytes the kappa-opioid agonist trans(+/-)-3,3-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]- benzeneacetamide methanesulfonate salt (U50488H) inhibited L-type calcium currents (ICa) as measured by the patch clamp technique in a dose-dependent fashion. The basal, as well as the isoprenaline and 8-Br-cAMP-stimulated, ICa(More)
This study aimed at finding simple algorithms to identify three different movements registered by accelerometer and to detect differences in the acceleration signals of people with and without visual impairments. The Tactile Acoustical Navigation and Information Assistant (TANIA) is construed to provide persons suffering from visual impairments support for(More)
We constructed miniaturized autoantigen arrays to perform large-scale multiplex characterization of autoantibody responses directed against structurally diverse autoantigens, using submicroliter quantities of clinical samples. Autoantigen microarrays were produced by attaching hundreds of proteins, peptides and other biomolecules to the surface of(More)
Mouse neuroblastoma x rat glioma hybrid cells (N x G, NG108-15) were used to study the mechanism of Ca(2+)-current (ICa) inhibition by 5-hydroxytryptamine (5-HT). 5-HT caused a dose-dependent decrease of ICa which was abolished by ICS 205-930 (10)(-8) M) while 2-methyl-5-HT was an agonist. Intracellular infusion of GDP beta S (50 microM) prevented the(More)
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