Juliana Serafim da Silveira

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INTRODUCTION Myocardial stiffness is an important determinant of cardiac function and is currently invasively and indirectly assessed by catheter angiography. This study aims to demonstrate the feasibility of quantifying right ventricular (RV) stiffness noninvasively using cardiac magnetic resonance elastography (CMRE) in dogs with severe congenital(More)
BACKGROUND Measurement of myocardial T2* is becoming widely used in the assessment of patients at risk for cardiac iron overload. The conventional breath-hold, ECG-triggered, segmented, multi-echo gradient echo (MGRE) sequence used for myocardial T2* quantification is very sensitive to respiratory motion and may not be feasible in patients who are unable to(More)
Maximal oxygen consumption ([Formula: see text]max) measured by cardiopulmonary exercise testing (CPX) is the gold standard for assessment of cardiorespiratory fitness. Likewise, cardiovascular magnetic resonance (CMR) is the gold standard for quantification of cardiac function. The combination of CPX and CMR may offer unique insights into cardiopulmonary(More)
Background Cardiac MR (CMR) is considered the gold standard to assess right ventricular (RV) function in different scenarios, including cases of congenital heart disease. Moreover, an MR-compatible treadmill coupled with Real Time (RT) CMR has been developed for stress testing, and may be an optimal choice in this setting. The aims of this study were to(More)
BACKGROUND Aortic stenosis (AS) is a common valvular disorder, and disease severity is currently assessed by transthoracic echocardiography (TTE). However, TTE results can be inconsistent in some patients, thus other diagnostic modalities such as cardiovascular magnetic resonance (CMR) are demanded. While traditional unidirectional phase-contrast CMR (1Dir(More)
Background Assessment of aortic valve stenosis (AVS) severity is crucial for valve replacement indication and is typically performed by transthoracic Doppler-echocardiography (TTE). However, TTE may be suboptimal in up to 30% of patients. Unidirectional through-plane phase-contrast magnetic resonance imaging (1Dir PC-MRI) is the most common MRI technique(More)
Background T2* measurement is widely used in the assessment of patients at risk for cardiac and hepatic iron overload (1,2). The conventional breath-hold, ECG-triggered, segmented, multi-echo gradient echo sequence (BH MGRE) used for myocardial T2* quantification (3) is very sensitive to respiratory motion and may not be feasible in patients who are unable(More)
Background Cardiac magnetic resonance elastography (CMRE) is a novel imaging technique to noninvasively quantify myocardial stiffness. Previous studies have demonstrated that excess interstitial fluid or fibrosis causes increased myocardial stiffness and also alter T1, T2 relaxation times, and myocardial extracellular volume fraction (ECV). Nonetheless, T1,(More)
Background Transthoracic Doppler-echocardiography (TTE) is the standard clinical method for diagnosis and staging of aortic stenosis (AS). AS staging is based on measurement of aortic peak velocity, transvalvular gradient, and calculation of aortic valve area. Unidirectional throughplane phase-contrast magnetic resonance imaging (1DPC-MRI) has been widely(More)