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Production and New Extraction Method of Polyketide Red Pigments Produced by Ascomycetous Fungi from Terrestrial and Marine Habitats
A pressurized liquid extraction technique was carried out in this study, allowing a greener and faster extraction step of the pigments, while preserving their chemical structures and bioactivities in comparison to conventional extraction processes.
Isolation of two novel purple naphthoquinone pigments concomitant with the bioactive red bikaverin and derivates thereof produced by Fusarium oxysporum
- Juliana Lebeau, T. Petit, P. Clerc, L. Dufossé, Y. Caro
- BiologyBiotechnology progress
- 21 November 2018
This is the first report of these two novel wild‐type purple naphthoquinones pigments along with bikaverin, where additionally, the culture conditions were put into perspective to optimize fermentation cultures and extraction process accordingly to the pigment/biomolecule desired.
Pigments and colorants from filamentous fungi
A Review of the Biotechnological Production of Methacrylic Acid
- Juliana Lebeau, J. Efromson, M. Lynch
- EngineeringFrontiers in Bioengineering and Biotechnology
- 20 March 2020
The potential of biobased routes from sugars to the large volume commodity, methacrylic acid, involving fermentation based bioprocesses is reviewed, including both academic as well as patent literature.
A critical review on the progress and challenges to a more sustainable, cost competitive synthesis of adipic acid
A review of recent developments and remaining challenges to the development of greener, cost competitive processes for adipic acid manufacture. Chemical and biotechnological processes from both…
Putative metabolic pathway for the bioproduction of bikaverin and intermediates thereof in the wild Fusarium oxysporum LCP531 strain
Along bikaverin production, the excretion of the toxin beauvericin as main extrolite exclusively in liquid medium containing complex nitrogen and carbon sources, as well as the isolation of ergosterol derivate in mycelial extracts, which have potential for pharmaceutical uses.
Alternative Extraction and Characterization of Nitrogen-Containing Azaphilone Red Pigments and Ergosterol Derivatives from the Marine-Derived Fungal Talaromyces sp. 30570 Strain with Industrial…
Interestingly, the bioproduction of these red pigments occurred only when complex organic nitrogen sources were present in the culture medium, which is important for the field of the selective production of Monascus-like azaphilone red Pigments for the industries.
Dynamic control over feedback regulation improves stationary phase fluxes in engineered E. coli.
This work reports the impact of dynamic control over two central metabolic enzymes: citrate synthase, and glucose-6-phosphate dehydrogenase, on stationary phase fluxes and identifies pyruvate oxidation via the pyruVate-ferredoxin oxidoreductase as a "central" metabolic pathway in stationary phase.
Two-stage dynamic deregulation of metabolism improves process robustness & scalability in engineered E. coli.
Dynamic control over feedback regulation identifies pyruvate-ferredoxin oxidoreductase as a central metabolic enzyme in stationary phase E. coli
The results identify pyruvate oxidation via the pyruVate-ferredoxin oxidoreductase as a “central” metabolic pathway in stationary phase E. coli, which coupled with ferredoxin reductase comprise a pathway whose physiologic role is maintaining NADPH levels.