Juliana Elisa Hidalgo Lopez

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T-cell large granular lymphocytic (T-LGL) leukemia after hematopoietic stem cell transplantation (SCT) is rare and its natural history and clinical outcome have not been well described. We report the clinical, morphologic, immunophenotypic, and molecular features of a case of donor-derived T-LGL leukemia in a 16-year-old man who received allogeneic SCT for(More)
Myelodysplastic syndromes (MDSs) are characterized by ineffective hematopoiesis and an increased risk of transformation. Few effective therapies are available for lower risk MDS patients, especially after the failure of hypomethylating agents. MDS progenitor cells are dependent on the nuclear factor-κB (NF-κB) for survival, which makes it an attractive(More)
Rashmi Kanagal-Shamanna, MD, Juliana E. Hidalgo Lopez, MD, Denái R. Milton, Hye Ryoun Kim, MD, PhD, Chong Zhao, MD, PhD, MS, Zhuang Zuo, MD, PhD, Michelle Janania Martinez, MD, Francesco Stingo, PhD, John Lee, MD, PhD, Rajyalakshmi Luthra, PhD, Elias J. Jabbour , MD, Guillermo Garcia-Manero, MD, L. Jeffrey Medeiros, MD and Carlos E. Bueso-Ramos, MD, PhD(More)
Up to 20% of patients with polycythemia vera have karyotypic abnormalities at the time of the initial diagnosis. However, the cytogenetic abnormalities in polycythemia vera have not been well characterized and their prognostic impact is largely unknown. In this study, we aimed to address these issues using a large cohort of polycythemia vera patients with(More)
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