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The three-dimensional structure of the cytostome-cytopharynx complex of Trypanosoma cruzi epimastigotes
TLDR
The cytopharynx of Trypanosoma cruzi epimastigotes is a dynamic structure, undergoing remodeling that is likely associated with endocytic activity and the preparation for cell division.
Morphological and Functional Aspects of Cytoskeleton of Trypanosomatids
TLDR
The principal finding of this review is that all approaches listed above enhance knowledge of trypanosomatids biology showing that cytoskeleton elements are essential to several important events throughout the protozoan life cycle.
The cytostome–cytopharynx complex of Trypanosoma cruzi epimastigotes disassembles during cell division
TLDR
3D models of the cytostome–cytopharynx complex of T. cruzi epimastigotes disassembles in mitosis, to assemble again in each daughter cell at the end of cell division, suggest that the microtubule quartet serves as a guide for new cytostOMS assembly.
Trypanosoma cruzi Epimastigotes Are Able to Manage Internal Cholesterol Levels under Nutritional Lipid Stress Conditions
TLDR
It is demonstrated that under nutritional lipid stress, epimastigotes preferentially mobilized reservosome lipid stocks, instead of lipid bodies, leading to the consumption of parasite cholesterol reservoirs and production of ergosterol, implying that exogenous cholesterol has a role in lipid reservoirs in epimastsigotes.
Lysosome-like compartments of Trypanosoma cruzi trypomastigotes may originate directly from epimastigote reservosomes
TLDR
It is demonstrated that the protease-containing compartments from metacyclic trypomastigotes may originate directly from the reservosomes of epimastigote, which store nutrients taken up during the intense endocytic activity exhibited by this developmental form.
3D Fib-sem structural insights into the architecture of sub-pellicular microtubules of trypanosoma cruzi epimastigotes.
TLDR
High-resolution 3D analyses revealed that certain microtubules of the SPMT end more prematurely than the neighboring ones, suggesting treadmilling/catastrophe events that have not yet been described in trypanosomatids.