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  • Cristina Martin-Fernandez, Juliana Bales, +4 authors Christopher J. Morrow
  • Biology, Medicine
  • Molecular cancer research : MCR
  • 2009 (First Publication: 1 June 2009)
  • In response to growth factors, class IA phosphoinositide 3-kinases (PI3K) phosphorylate phosphatidylinositol-4,5-bisphosphate, converting it to phosphatidylinositol-3,4,5-trisphosphate to activateContinue Reading
  • Heather Keen, Bernd J. Pichler, +9 authors Stephen Robert Wedge
  • Medicine
  • Molecular Imaging and Biology
  • 2011 (First Publication: 1 June 2012)
  • PurposeThe aim of this study is to assess the variability of 2-deoxy-2-[18F]fluoro-d-glucose ([18F]-FDG) and 3′-deoxy-3′-[18F]-fluorothymidine ([18F]-FLT) uptake in pre-clinical tumor models andContinue Reading
  • Cristina Fernández, Juliana Bales, Arkadiusz Welman, Caroline Dive, Christopher J. Morrow
  • Biology
  • 2007 (First Publication: 1 November 2007)
  • C13 Class IA phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that, in response to growth factor stimulation, phosphorylate PtdIns(4,5)P2, converting it to PtdIns(3,4,5)P3. The generation ofContinue Reading