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Adhesion-mediated cytoskeletal remodeling is controlled by the direct scaffolding of Src from FAK complexes to lipid rafts by SSeCKS/AKAP12
Metastatic cell migration and invasion are regulated by altered adhesion-mediated signaling to the actin-based cytoskeleton via activated Src–FAK complexes. Src-suppressed C-kinase substrate (SSeCKS,Expand
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Control of Protein Kinase C Activity, Phorbol Ester-induced Cytoskeletal Remodeling, and Cell Survival Signals by the Scaffolding Protein SSeCKS/GRAVIN/AKAP12*
Background: SSeCKS/GRAVIN/AKAP12 is a major protein kinase C substrate and binding protein. Results: SSeCKS binding of PKC via two homologous domains is required for attenuation of PKC activity andExpand
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