Julian J. Nussbaum
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GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.
- Deeksha Gambhir, S. Ananth, +9 authors P. Martin
- Biology, Medicine
- Investigative ophthalmology & visual science
- 24 April 2012
PURPOSE Retinal pigment epithelium (RPE) expresses GPR109A, a receptor for the vitamin niacin and the ketone body β-hydroxybutyrate (β-HB). Because diabetes results in elevated levels of β-HB, here… Expand
Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury
Aims/hypothesisDiabetic retinopathy, the leading cause of blindness in working-age Americans, is characterised by reduced neurotrophic support and increased proinflammatory cytokines, resulting in… Expand
Historic perspectives. Macular yellow pigment. The first 200 years.
Since 1782 there has been continuing controversy concerning the curious central coloration referred to as "macular yellow," but no cumulative source of information on the subject exists. This paper… Expand
Pronerve Growth Factor Induces Angiogenesis via Activation of TrkA: Possible Role in Proliferative Diabetic Retinopathy
- Sally L. Elshaer, M. Abdelsaid, +4 authors A. El-Remessy
- Journal of diabetes research
- 12 August 2013
Proliferative diabetic retinopathy (PDR) is the leading cause of blindness in working age Americans. We demonstrated that diabetes disturbs the homeostasis of nerve growth factor (NGF) resulting in… Expand
Pseudomonas pseudomallei in an anopthalmic orbit.
A 21-year old man sustained multiple facial fractures and skin lacerations during an automobile accident, with resultant necrosis of the left upper eyelid and exposure of the cornea. Bacterial and… Expand
Virtual reality in ophthalmology training.
- Y. Khalifa, D. Bogorad, V. Gibson, J. Peifer, Julian J. Nussbaum
- Survey of ophthalmology
- 1 May 2006
Current training models are limited by an unstructured curriculum, financial costs, human costs, and time constraints. With the newly mandated resident surgical competency, training programs are… Expand
Angiotensin II and retinal pericytes migration.
- J. A. Nadal, G. Scicli, L. A. Carbini, Julian J. Nussbaum, A. G. Scicli
- Biology, Medicine
- Biochemical and biophysical research…
- 20 December 1999
Angiotensin II (Ang II) appears to participate in the regulation of neovascularization processes in the retina. Migration of perimural cells such as pericytes plays a key role in regulation of… Expand
Long-term visual morbidity of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
BACKGROUND Patient survival with the acquired immune deficiency syndrome (AIDS) and cytomegalovirus (CMV) retinitis is increasing because of earlier diagnosis and improved medical therapy. Visual… Expand
Autosomal dominant crystalline dystrophy.
- B. Richards, D. Brodstein, J. Nussbaum, J. Ferencz, K. Maeda, L. Weiss
- 1 May 1991
A black woman was identified with a tapetoretinal degeneration with sparkling intraretinal crystals, retinal pigment epithelial and choroidal atrophy, night blindness, color vision abnormalities, and… Expand
Pseudomonas pseudomallel in an Anophthalmic Orbit
A 21-year-old man sustained multiple facial fractures and skin lacerations during an automobile accident, with resultant necrosis of the left upper eyelid and exposure of the cornea. Bacterial and… Expand