Julia Scheffler

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AIMS/HYPOTHESIS We used Laser Doppler Fluximetry (LDF) to define "normal" endothelial function in a large cohort of healthy children and adolescents and to evaluate skin microcirculation in paediatric patients with type 1 diabetes mellitus. METHODS LDF was performed in 102 healthy children (12.8 ± 3.3 years of age; 48 male) and 68 patients (12.9 ± 3.3(More)
The zinc finger transcription factor Egr-1 controls many biological functions in the nervous system, including neuronal plasticity, cell death and proliferation. Egr-1 connects cellular signaling cascades with changes of the gene expression pattern. Here, we show that epidermal growth factor (EGF) and carbachol stimulated the biosynthesis of Egr-1 in human(More)
Myeloid neoplasia has been studied extensively in human beings but has not been reported in macaques. A 2-year-old female rhesus macaque that was experimentally exposed to lead as a neonate, was noted to have immature circulating myelocytic cells, including 1% blasts, and normocytic normochromic anemia on a blood sample obtained for monthly health(More)
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