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Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1
The transcription factor PU.1 is crucial for the development of many hematopoietic lineages and its binding patterns significantly change during differentiation processes. However, the ‘rules’ forExpand
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Functional Characterization of the Binding Properties of the Hematopoietic Transcription Factor PU.1
Transcription factors are defined through their ability to recognize and bind specific sequence motifs in genomic DNA. Such sequence motifs are very small compared to the length of the human genome,Expand