Julia Louise Wunderlich

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OBJECTIVES 1) To investigate the unaided and aided speech perception abilities of children with auditory neuropathy (AN) and to compare their performance to children with sensorineural hearing loss. 2) To establish whether cortical event related potentials (ERPs) could be recorded in children with AN, and to determine the relationship between the presence(More)
The aim of this study was to evaluate the maturation of the cortical auditory evoked potential (CAEP) in humans. The participants in this experiment were 10 newborns (<7 days), 19 toddlers (13-41 months), 20 children (4-6 years) and 9 adults (18-45 years). CAEPs were obtained in response to low (400 Hz) and high (3000 Hz) tones and to the word token /baed/,(More)
Genetic hearing impairment affects approximately 1/2000 live births. Mutations in one gene, GJB2, coding for connexin 26 cause 10%–20% of all genetic sensorineural hearing loss. Mutation analysis in the GJB2 gene and audiology were performed on 106 families presenting with at least one child with congenital hearing loss. The families were recruited from a(More)
This paper reviews our current understanding of the development of the obligatory cortical auditory evoked potential (CAEP) components P1, N1, P2, and N2. Firstly, the adult CAEP is briefly reviewed with respect to its morphology, neural generators and stimulus-dependence. Secondly, age-related changes occurring from the newborn period through childhood and(More)
PURPOSE OF REVIEW The audiological applications of cortical auditory evoked potentials are reviewed. Cortical auditory evoked potentials have some advantages compared with more commonly used techniques such as the auditory brainstem response, because they are more closely tied to perception and can be evoked by complex sounds such as speech. These response(More)
This study investigated, first, the effect of stimulus frequency on mismatch negativity (MMN), N1, and P2 components of the cortical auditory event-related potential (ERP) evoked during passive listening to an oddball sequence. The hypothesis was that these components would show frequency-related changes, reflected in their latency and magnitude. Second,(More)
OBJECTIVE To determine (1) the prevalence and nature of connexin 26 mutations in a cohort of Australian children with non-syndromic hearing loss, and (2) the carrier frequency of the common connexin 26 mutation (35delG) in the general population. DESIGN A cohort, case-finding study. Mutation analysis was performed on DNA extracted from white blood cells,(More)
The near field monitoring of an auditory evoked response from the cochlear (electrocochleography) is a tried and trusted clinical tool. Conventional techniques for performing electrocochleography are cumbersome to use and frequently uncomfortable for the patient. We present a simple, modified technique which provides more flexibility with regard to where(More)
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