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A 42-year-old woman developed severe neck pain 20 hours postpartum. She had cervical spondylitis from an accident 15 years earlier. An elevated sedimentation rate was the only abnormal laboratory finding. Vertebral osteomyelitis was diagnosed by magnetic resonance imaging 12 days postpartum. She underwent radical debridement of C5 and C6 with anterior… (More)
Two patients who developed hepatic and splenic amebic abscesses during pregnancy are reported. The frequency of incorrect diagnosis in patients with these conditions is stressed. Factors that influence the course and outcome of amebiasis in pregnancy are discussed.
A 13-year-old girl with evidence of hyperestrinism had a right ovarian tumor removed. This neoplasm was composed predominantly of granulosa cells and exhibited some changes of luteinization. The neoplastic cells displayed an investment of basement membrane material which was closely related to fibrillar collagen within the tumor. Scattered throughout the… (More)
In the course of industrial-scale manufacture of unfermented rhubarb fruit juice, the deacidifying agent CaCl2 was confused with the disinfectant NH4HF2. Hence, fluoride in a quantity of up to 0.6 g/l was present in the unfermented fruit juice. Signs of acute fluoride poisoning were therefore seen after ingestion of the rhubarb juice. The incident as well… (More)
Identification of patients with increased risk of 5-fluorouracil (5-FU)-related toxicity is an important challenge for cancer treatment. Research often focus on dihydropyrimidine dehydrogenase (DPYD) deficiency in this context. However, patients with normal DPYD activity may also develop life-threatening 5-FU adverse effects. DPYD initiates the catabolic… (More)