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- Rajen J Mody, Arlene H Naranjo, +11 authors Rochelle Bagatell
- The Lancet. Oncology
- 2017
BACKGROUND
Outcomes for children with relapsed and refractory neuroblastoma are dismal. The combination of irinotecan and temozolomide has activity in these patients, and its acceptable toxicity… (More)
- Jennifer A Oberg, Julia Glade Bender, +5 authors Mitchell S Cairo
- Bone Marrow Transplantation
- 2013
The objective of this study was prospectively to investigate the health-related quality of life (HRQOL) of 80 pediatric recipients of allo-SCT for malignant and non-malignant diseases. The PedsQL 4.0… (More)
- Susan J Hsiao, Matthias A Karajannis, +4 authors James H. Garvin
- Cold Spring Harbor molecular case studies
- 2017
Pleomorphic xanthoastrocytoma (PXA) is a World Health Organization (WHO) Grade II glioma occurring primarily in children and young adults. Most PXAs harbor the known activating mutation BRAF V600E.… (More)
- Patrick J Leavey, Julia Glade Bender, +5 authors Neyssa Marina
- 2010
9552 Background: The importance of angiogenesis in EWS has been well explored and activity of angiogenesis inhibitors observed in relevant pre-clinical models. The combination of topotecan and… (More)
- Brigitte C Widemann, E Fox, +7 authors Susan M. Blaney
- Journal of clinical oncology : official journal…
- 2009
10012 Background: Sorafenib, an oral multitargeted kinase inhibitor, is indicated for treatment of adults with refractory renal cell or hepatocelluar carcinoma. We performed a phase I trial to… (More)
- Stephen Sands, Elena J. Ladas, +6 authors Julia Glade Bender
- Supportive Care in Cancer
- 2016
BackgroundVincristine is an integral treatment component of many childhood tumors with potentially dose-limiting sensory and/or motor neuropathy. Results from a pilot study on the incidence of… (More)
- Brigitte C Widemann, AeRang Kim, +9 authors Susan M. Blaney
- 2012
Purpose
To determine the dose-limiting toxicities (DLT), maximum tolerated dose (MTD), pharmacokinetics and pharmacodynamics of sorafenib in children with refractory extracranial solid tumors and… (More)
- Julie R. Park, Douglas S Hawkins, +7 authors Susan M. Blaney
- 2010
9530 Background: Interference with vascular endothelial growth factor (VEGF)-mediated angiogenesis and vascular permeability may be beneficial in controlling the growth and metastatic spread of… (More)
- Yoav H Messinger, Paul S. Gaynon, +7 authors Bruce C Bostrom
- 2008
The outcome of relapsed ALL remains very poor, and many re-induction regimens are highly toxic. We report here the Phase I component of a Phase I/II study of bortezomib added to 4-drug induction with… (More)
- Kiersten W Ricci, Adrienne M Hammill, +7 authors Denise M Adams
- Pediatric blood & cancer
- 2019
BACKGROUND
Generalized lymphatic anomaly (GLA) and Gorham-Stout disease (GSD) are rare complicated lymphatic malformations that occur in multiple body sites and are associated with significant… (More)