Julia F. Kuder

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OBJECTIVE The objective of this study was to test the hypothesis that community-based environmental change intervention prevents undesirable weight gain in children. METHOD The method used in this study was a two-year, non-randomized, controlled trial (2003-2005) using community-based participatory methodology in three diverse cities in Massachusetts: one(More)
OBJECTIVES We tested a community-based intervention designed to reduce cardiovascular disease risk in sedentary midlife and older women who were overweight or obese. METHODS In a randomized controlled trial conducted in 8 counties in Arkansas and Kansas, counties were assigned to the intervention (a 12-week twice-weekly heart health program) group or to(More)
BACKGROUND Evolocumab is a monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and lowers low-density lipoprotein (LDL) cholesterol levels by approximately 60%. Whether it prevents cardiovascular events is uncertain. METHODS We conducted a randomized, double-blind, placebo-controlled trial involving 27,564 patients with(More)
BACKGROUND Changes in the school food environment are a logical target to prevent childhood overweight. We describe the food service component of a 2-year research intervention to prevent excess weight gain in children. CONTEXT The goals of the food service component were to improve the presentation and nutrient quality of school meals and to incorporate(More)
BACKGROUND Despite the recognized health benefits, few older women participate in strength-training exercises. METHODS The purpose of this study was to examine factors related to older women's adherence to strength training after participation in the StrongWomen Program, a nationally disseminated community program. Adherence was defined as > or =4 months(More)
BACKGROUND Strength training (ST) is an important health behavior for aging women; it helps maintain strength and function and reduces risk for chronic diseases. This study assessed change in physical fitness following participation in a ST program implemented and evaluated by community leaders. METHOD The StrongWomen Program is a nationally disseminated,(More)
AIMS We evaluated the relationship of renal function and ischaemic and bleeding risk as well as the efficacy and safety of ticagrelor in stable patients with prior myocardial infarction (MI). METHODS AND RESULTS Patients with a history of MI 1-3 years prior from PEGASUS-TIMI 54 were stratified based on estimated glomerular filtration rate (eGFR), with <60(More)
BACKGROUND New oral anticoagulants for stroke prevention in atrial fibrillation were developed to be given in fixed doses without the need for the routine monitoring that has hindered usage and acceptance of vitamin K antagonists. A concern has emerged, however, that measurement of drug concentration or anticoagulant activity might be needed to prevent(More)
PURPOSE The purpose of this study was to assess anthropometry, physical fitness, and serum glucose and lipid levels in college students and to determine the relative impact of fitness level compared with body composition on blood chemistries related to metabolic syndrome. METHODS College students (n = 564; means +/- SD: age = 19.4 +/- 1.1 yr)(More)
BACKGROUND Edoxaban, an oral factor Xa inhibitor with 50% renal clearance, was noninferior to well-managed warfarin for stroke or systemic embolism (S/SE) prevention and reduced bleeding in patients with atrial fibrillation. We evaluated the efficacy and safety of edoxaban versus warfarin across the range of baseline creatinine clearance (CrCl) in the(More)