Jules M. Pieters

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NMR studies were carried out on various equimolar mixtures consisting of a combination of oligomers: d(ACGGCT) (I). d(pACGGCT) (Ia), d(TGCAGT) (II), d(AGCCGTACTGCA) (III), d(TGCAGTACGGCT) (IV). It is shown that I + II + III (MI) and Ia + II + III (M2) form stable duplexes with nicks in the centre of the respective double helices. A close analysis of the(More)
Nuclear magnetic resonance (NMR) and model-building studies were carried out on the hairpin form of the octamer d(CGaCTAGCG) (aC = arabinofuranosylcytosine), referred to as the TA compound. The nonexchangeable protons of the TA compound were assigned by means of nuclear Overhauser effect spectroscopy (NOESY) and correlated spectroscopy (COSY). From a(More)
  • J M Pieters
  • 1981
A reaction-time (RT) experiment was carried out in which five groups consisting of subjects with various degrees of left and right handedness, participated. The words left and right were presented binaurally, one at a time, either to the left or to the right side, implying four presentation modes. The two interfering presentation modes are regarded as(More)
This paper aims to answer two questions. The first is how screen captures in software manuals should be used to support learning. Four functions of screen captures in software manuals are presented. Three studies report the influence of these functions on the effectiveness and efficiency of the learning process. The second question is how users of visual(More)
In this article, we describe an investigation into the diagnostic activities of practicing clinical psychologists. Two questionnaires were filled in by 313 psychologists. One group of psychologists (N = 175) judged the necessity of diagnostic activities; the other group (N = 138) selected the activities they would actually perform. Results showed that more(More)
A clear and concise description and clinical interpretation of the cavernous sinus syndrome are lacking. Pathological changes in or around the cavernous sinus may lead to failure of eye muscle nerves and of one or more branches of the trigeminal nerve. The clinical signs of the cavernous sinus syndrome are combinations of failure of these cranial nerves(More)
In the present study, the effects of two instructional strategies on the retention and transfer of procedures of different difficulty level were investigated. Difficulty level was manipulated by providing a different number of cues during training. The instructional strategies differed with respect to the amount of contextual interference. Sixty-four(More)
Preface It is a little weird that, after finishing the thesis, there is still some writing to be done. First of all, I would like to thank Ton and Robert. Ton started the whole process and persistently ensured it kept on moving in the right direction. Robert excelled at getting the product right. Our conversations were on topic most of the time, although we(More)
Marleen Groenier, Vos R. J. Beerthuis, Jules M. Pieters, Cilia L. M Witteman, Jan A. Swinkels Instructional Technology, University of Twente, Enschede, The Netherlands; Psychiatry, GGZ inGeest, Amstelveen, The Netherlands; Curriculum Design & Educational Innovation, University of Twente, Enschede, The Netherlands; Diagnostic Decision Making, Radboud(More)
Diabetic ketoacidosis presenting as acute abdomen. – Three patients , two women aged 21 and 67 and a man aged 43 years, presented at the emergency department with diabetic ketoacido-sis and abdominal symptoms mimicking an acute abdominal condition. In two of them laparotomy was performed which proved to be negative. Abdominal symptoms resolved after(More)