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Amyloid-beta (Abeta) immunization efficiently reduces amyloid plaque load and memory impairment in transgenic mouse models of Alzheimer's disease (AD). Active Abeta immunization has also yielded… (More)
Introduction: Acquired resistance (AQR) continues to be source of treatment failure in EGFR inhibitor therapy and subsequent second-line strategies. In this study, AQR to the PI3K/mTOR inhibitor… (More)