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BACKGROUND The Navigation Guide methodology was developed to meet the need for a robust method of systematic and transparent research synthesis in environmental health science. We conducted a case study systematic review to support proof of concept of the method. OBJECTIVE We applied the Navigation Guide systematic review methodology to determine whether(More)
BACKGROUND In contrast to current methods of expert-based narrative review, the Navigation Guide is a systematic and transparent method for synthesizing environmental health research from multiple evidence streams. The Navigation Guide was developed to effectively and efficiently translate the available scientific evidence into timely prevention-oriented(More)
BACKGROUND The Navigation Guide is a novel systematic review method to synthesize scientific evidence and reach strength of evidence conclusions for environmental health decision making. OBJECTIVE Our aim was to integrate scientific findings from human and nonhuman studies to determine the overall strength of evidence for the question "Does developmental(More)
Environmental health hazard assessments are routinely relied upon for public health decision-making. The evidence base used in these assessments is typically developed from a collection of diverse sources of information of varying quality. It is critical that literature-based evaluations consider the credibility of individual studies used to reach(More)
In this comment, we summarize several scientific concerns with the recently published systematic review from O'Connor and colleagues that examined the relationship between proximity to animal-feeding operations and health of individuals in nearby communities. The authors utilized a bias tool not designed for environmental health research, erroneously(More)
Implementing systematic review techniques in chemical risk assessment: Challenges, opportunities and recommendations Paul Whaley , Crispin Halsall ⁎, Marlene Ågerstrand , Elisa Aiassa , Diane Benford , Gary Bilotta , David Coggon , Chris Collins , Ciara Dempsey , Raquel Duarte-Davidson , Rex FitzGerald , Malyka Galay-Burgos , David Gee , Sebastian Hoffmann(More)
BACKGROUND Exposure to ambient air pollution is widespread and may be detrimental to human brain development and a potential risk factor for Autism Spectrum Disorder (ASD). We conducted a systematic review of the human evidence on the relationship between ASD and exposure to all airborne pollutants, including particulate matter air pollutants and others(More)
The purpose of the present study was to comprehensively evaluate available golf course water quality data and assess the extent of impacts, as determined by comparisons with toxicologic and ecologic reference points. Most water quality monitoring studies for pesticides have focused on agriculture and often the legacy chemicals. There has been increased(More)
OBJECTIVE Glomerular filtration rate (GFR) may influence concentrations of biomarkers of exposure and their etiologic significance in observational studies of associations between environmental contaminants and fetal growth. It is unknown whether the size of a developing fetus affects maternal GFR such that a small fetus leads to reduced plasma volume(More)
Private wells serving fewer than 25 people are federally unregulated, and their users may be exposed to naturally occurring agents of concern such as arsenic and radionuclides, as well as anthropogenic contaminants. The Centers for Disease Control and Prevention's Clean Water for Health Program works to protect private wells and prevent adverse health(More)