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We propose a novel convex relaxation of sparse principal subspace estimation based on the convex hull of rank-d projection matrices (the Fantope). The convex problem can be solved efficiently using alternating direction method of multipli-ers (ADMM). We establish a near-optimal convergence rate, in terms of the spar-sity, ambient dimension, and sample size,(More)
BACKGROUND Despite the important role that family caregivers play in providing emotional and practical support to cancer patients, relatively little is known about the family caregiver's role in treatment decision-making (TDM). We sought to investigate patients' and family caregivers' preferences for and experiences of family involvement in TDM and factors(More)
INTRODUCTION Guidelines for management of non-small cell lung cancer (NSCLC) strongly recommend EGFR mutation testing. These recommendations are particularly relevant in Asians that have higher EGFR mutation prevalence. This study aims to explore current testing practices, logistics of testing, types of EGFR mutation, and prevalence of EGFR mutations in(More)
BACKGROUND Diabetes may affect vascular autoregulation of the retina and optic nerve and may be associated with an increased risk of glaucoma,but the association of prediabetes, insulin resistance, markers of glucose metabolismwith glaucoma has not beenevaluated in general population samples. OBJECTIVE To examine the relation between diabetes,(More)
INTRODUCTION Although it is known that at comparable body mass index (BMI) levels Asian Americans have a higher prevalence of high blood pressure, heart disease, and type 2 diabetes than whites, little is known about the social, behavioral, and cultural factors associated with obesity risk in this population. METHODS A cross-sectional analysis of the 2003(More)
BACKGROUND Serum bilirubin may have potent antioxidant and cytoprotective effects. Serum bilirubin levels are inversely associated with several cardiovascular and metabolic endpoints, but their association with nonalcoholic fatty liver disease (NAFLD) has not been investigated except for a single cross-sectional study in a pediatric population. We assessed(More)
BACKGROUND Regardless of improved survival rate, negative images and myths about cancer still abound. Cancer stigma may reduce patients' life opportunities resulting in social isolation, decreased level of emotional well-being, and poor health outcomes. This study was aimed to evaluate public attitudes toward cancer and cancer patients and people's(More)
BACKGROUND In Korea, nicotine replacement therapy (NRT) has been widely used in government-led, public health center-based smoking cessation services since 2004 and varenicline has become available from 2007 but without reimbursement. In this study which used a series of nationwide cross-sectional surveys in Korea performed from 2005 to 2011, we examined(More)
PURPOSE To examine the longitudinal association between age and intraocular pressure (IOP) in a large sample of Korean men and women. METHODS We conducted a prospective cohort study of 274,064 young and middle-aged Korean adults with normal fundoscopic findings, following them from January 1, 2002, to February 28, 2010. Health exams were scheduled(More)
BACKGROUND Physical activity may be an effective way of preventing or attenuating menopause-related symptoms, and it has been shown to improve quality of life in menopausal women. However, there have been some inconsistencies regarding between exercise and menopausal symptoms, and study investigating this association has been scarce in Korea. In this study,(More)