Juergen Stech

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In this paper we propose a stochastic model based on the branching process for estimation and comparison of the mutation rates in proliferation processes of cells or microbes. We assume in this model that cells or microbes (the elements of a population) are reproduced by generations and thus the model is more suitably applicable to situations in which the(More)
Reassortment of influenza A virus genes enables antigenic shift resulting in the emergence of pandemic viruses with novel hemagglutinins (HA) acquired from avian strains. Here, we investigated whether historic and contemporary avian strains with different replication capacity in human cells can donate their hemagglutinin to a pandemic human virus. We(More)
permits non-commercial use, distribution and reproduction of the article, provided the original work is appropriately acknowledged with correct citation details. Since the first appearance of the pandemic (H1N1) 2009 virus many efforts have been made to monitor the changes of the virus at molecular level with the aim to early detect mutations which could(More)
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