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The interpretation of experimental results from functional medical imaging is complicated by intersubject and interspecies differences in airway geometry. The application of computational models in understanding the significance of these differences requires methods for generation of subject-specific geometric models of the bronchial airway tree. In the(More)
The segmentation of the human airway tree from volumetric computed tomography (CT) images builds an important step for many clinical applications and for physiological studies. Previously proposed algorithms suffer from one or several problems: leaking into the surrounding lung parenchyma, the need for the user to manually adjust parameters, excessive(More)
This paper describes a framework for establishing a reference airway tree segmentation, which was used to quantitatively evaluate fifteen different airway tree extraction algorithms in a standardized manner. Because of the sheer difficulty involved in manually constructing a complete reference standard from scratch, we propose to construct the reference(More)
Modern multislice X-ray CT scanners provide high-resolution volumetric image data containing a wealth of structural and functional information. The size of the volumes makes it more and more difficult for human observers to visually evaluate their contents. Similar to other areas of medical image analysis, highly automated extraction and quantitative(More)
Matching of corresponding branchpoints between two human airway trees, as well as assigning anatomical names to the segments and branchpoints of the human airway tree, are of significant interest for clinical applications and physiological studies. In the past, these tasks were often performed manually due to the lack of automated algorithms that can(More)
A method for computationally efficient skeletonization of three-dimensional tubular structures is reported. The method is specifically targeting skeletonization of vascular and airway tree structures in medical images but it is general and applicable to many other skeletonization tasks. The developed approach builds on the following novel concepts and(More)
The segmentation of the human airway tree from volumetric multidetector-row computed tomography images is an important prerequisite for many clinical applications and physiologic studies. We present a new airway segmentation method based on fuzzy connectivity. Small adaptive regions of interest are used that follow the airway branches as they are segmented.(More)
A method for quantitative assessment of tree structures is reported allowing evaluation of airway or vascular tree morphology and its associated function. Our skeletonization and branch-point identification method provides a basis for tree quantification or tree matching, tree-branch diameter measurement in any orientation, and labeling individual branch(More)
A highly automated method for the identification and quantization of maximum blood velocity curves from Doppler ultrasound flow diagrams is presented. The method uses an image processing scheme to analyze video-recorded image sequences of flow diagrams. The sequences are acquired, a sequence of images relating to chronological cardiac cycles is extracted,(More)