Judy Longsdorf

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Severe hypoproteinemia often accompanies the development of graft-versus-host disease of the intestine in allogeneic bone marrow transplant patients. To determine whether or not protein loss occurs across the intestinal mucosa in this severe diarrheal illness, we measured fecal alpha 1-antitrypsin once per week in 24-h stool specimens from 25 consecutive(More)
The role of oxidants in hepatocyte injury is currently being considered. Infants and children with α1AT deficiency are more prone to hepatocyte injury than adults. We have begun in vitro investigations of the cells closest to hepatocytes (Kupffer cells) in regards to their extracellular superoxide production in the presence or absence of an uninhibited(More)
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