The lipid composition of Bacillus megatherium was studied by extracting the lipids with chloroform-methanol (2:1) and purified by the Folch method. Lipids were fractionated by DEAE-cellulose column chromatography. Lipid classes we're determined by thin layer chromatography. Diglycerides, hydroxy-fatty acids and free fatty acids were qualitatively determined… (More)
Michael Wallerstein for comments and suggestions on that version of the paper, and apologize for the over 22 year gap in revisions. Nicholson and Ranganath contributed the empirical sections of this paper, and thank James Hamilton for helpful advice. The authors are listed alphabetically.
Intravenous injections of 50 micrograms corticotropin-releasing factor (CRF) to four normal men at 0900 and 2300 h were followed by significant plasma ACTH and cortisol elevations, without changes in GH and PRL concentrations. The responses were more easily assessed late in the evening than in the morning, when they were superimposed upon the spontaneous… (More)
Intermittent high-frequency electrical stimulation of the caudate nucleus induces contralateralhead-turning in rats. The anti-Parkinson drugs, L-dopa, amantadine and apomorphine, raise the threshold for or completely inhibit head-turning. There was a high correlation between the predicted clinical potency and these drugs based on inhibition of head-turning… (More)
Some narcotic drugs have been reported to produce increases in muscle tone in rats. In our laboratory we have found that etonitazine produces a 'lead-pipe' rigidity of the trunk and limb musculature. The reported studies were conducted to characterize etonitazine-induced rigidity more fully, to compare the degree of rigidity with that produced by morphine,… (More)