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  • Judith Niesen, Christoph W. Stein, +5 authors Stefan Barth
  • Biology, Medicine
  • Journal of Cancer Research and Clinical Oncology
  • 2015 (First Publication: 22 April 2015)
  • PurposeThe epidermal growth factor receptor (EGFR) is overexpressed in many solid tumors. EGFR-specific monoclonal antibodies (mAbs), such as cetuximab and panitumumab, have been approved for theExpand
  • Judith Niesen, Grit Hehmann-Titt, +4 authors Christoph W. Stein
  • Medicine, Biology
  • Cancer letters
  • 2016 (First Publication: 1 May 2016)
  • Human cytolytic fusion proteins (hCFPs) offer a promising immunotherapeutic approach for the treatment of solid tumors, avoiding the immunogenicity and undesirable side-effects caused by immunotoxinsExpand
  • Mira Woitok, Diana Klose, +9 authors Katharina Kolberg
  • Medicine, Biology
  • Cancer letters
  • 2016 (First Publication: 28 October 2016)
  • Antibody-drug conjugates (ADCs) combine the potency of cytotoxic drugs with the specificity of monoclonal antibodies (mAbs). Most ADCs are currently generated by the nonspecific conjugation ofExpand