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Iron deficiency is a known complication of achlorhydria and may precede the development of pernicious anemia. Among 160 patients with autoimmune gastritis identified by hypergastrinemia and strongly positive antiparietal antibodies, we explored the overlap between 83 subjects presenting with iron deficiency anemia (IDA), 48 with normocytic indices, and 29(More)
Previous studies have suggested that D-dimer testing reliably selects patients for whom duplex sonography should be performed for diagnosis of deep vein thrombosis (DVT). However, the interassay correlation is poor. Therefore, we tested four D-dimer methods for their ability to rule out DVT, including the Miniquant test, a new D-dimer assay method.(More)
Infections due to Salmonella spp. are common and their incidence appears to be increasing in many countries [1, 2]. Non-typhoidal Salmonella infections are usually associated with contaminated food products [3]. Salmonellosis may present in five forms: asymptomatic chronic carrier state, gastroenteritis, enteric fever, bacteremia and extraintestinal(More)
Markedly elevated serum IgE levels have been noted following allogeneic bone marrow transplantation (BMT) and have been correlated with graft-v-host disease (GVHD) in several studies. To investigate this phenomenon, we measured serum IgE levels in 387 allogeneic, 143 autologous, and 21 syngeneic BMT recipients before and at intervals after BMT. As a(More)
A male 34-year-old patient with aggressive diffuse malignant lymphoma was hospitalized for treatment. Because of high likelihood of CNS involvement, intrathecal methotrexate (MTX) 15 mg was administered with hydrocortisone 100mg. Shortly after the intrathecal injection the patient became agitated, and complained of severe low back pain and 2h later he(More)
Although full blood counts (FBC) are among the most commonly performed laboratory tests, the contribution of routine FBCs to the diagnosis of new problems is controversial. This study represents a unique linkage of a consultant haematology team, reviewing all abnormal blood counts, to an organization providing ambulatory health care to 350,000 patients. The(More)
Hyperammonemic Encephalopathy in Multiple Myeloma Multiple myeloma is a neoplastic monoclonal proliferation of bone marrow plasma cells characterized by lytic bone lesions, plasma cell accumulation in the bone marrow, and the presence of mono­ clonal protein in the serum and urine. Disturbances in level of consciousness are frequent in MM, with(More)