Judith Gaffney

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Experiments have been designed to test the hypothesis that soluble mediator production and T-cell-mediated cytotoxicity are necessarily related phenomena, and that soluble mediators may be involved in the mechanism of cytolysis. To this end, agents known to inhibit T-cell-mediated lysis in vitro have been studied for their effects on the production of two(More)
The echinoderms Asterias rubens and Marthasterias glacialis metabolize injected [4-(14)C]progesterone to give labelled 3beta-hydroxy-5alpha-pregnan-20-one and 3beta,6alpha-dihydroxy-5alpha-pregnan-20-one. These radioactive products are converted by the animals into conjugated forms that are soluble in aqueous methanol, and which have mobilities on t.l.c.(More)
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