Judith Birkenfeld

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OBJECTIVE To quantify 3-dimensionally the anterior segment geometry, biometry, and lens position and alignment in patients before and after implantation of the Crystalens-AO (Bausch & Lomb, Rochester, NY) accommodating intraocular lens (A-IOL). DESIGN Prospective, observational study. PARTICIPANTS Ten patients (20 eyes) with cataract before and after(More)
PURPOSE To evaluate the objective accommodative response, change of aberrations, and depth of focus in eyes implanted with the Crystalens accommodative intraocular lens (IOL) at different accommodative demands. DESIGN Prospective, observational study. METHODS Eleven cataract patients (22 eyes) who underwent implantation of a Crystalens accommodative(More)
PURPOSE To estimate changes in surface shape and gradient refractive index (GRIN) profile in primate lenses as a function of accommodation. To quantify the contribution of surface shape and GRIN to spherical aberration changes with accommodation. METHODS Crystalline lenses from 15 cynomolgus monkeys were studied in vitro under different levels of(More)
The optical properties of the crystalline lens are determined by its shape and refractive index distribution. However, to date, those properties have not been measured together in the same lens, and therefore their relative contributions to optical aberrations are not fully understood. The shape, the optical path difference, and the focal length of ten(More)
PURPOSE To estimate the contribution of 3-dimensional (3D) lens geometry and gradient refractive index (GRIN) to the lens spherical aberration (SA) with age. METHODS A total of 35 donor human lenses (19-71 years) were imaged with 3D-spectral optical coherence tomography (sOCT). Paraxial and nonparaxial back focal length were measured with laser ray(More)
Quantitative 3-D Optical Coherence Tomography was used to measure surface topography of 36 isolated human lenses, and to evaluate the relationship between anterior and posterior lens surface shape and their changes with age. All lens surfaces were fitted to 6th order Zernike polynomials. Astigmatism was the predominant surface aberration in anterior and(More)
PURPOSE We estimated the contribution of the gradient refractive index (GRIN) and lens surfaces to lens astigmatism and lens astigmatic angle as a function of age in human donor lenses. METHODS Human lenses were imaged, ex vivo, with 3D-spectral optical coherence tomography (OCT) and their back focal length was measured using laser ray tracing. The(More)
Mengchan Sun Alberto de Castro Sergio Ortiz Pablo Perez-Merino Judith Birkenfeld Susana Marcos Instituto de Óptica “Daza de Valdés” Consejo Superior de Investigaciones Científicas Serrano 121 28006 Madrid, Spain E-mail: susana@io.cfmac.csic.es Abstract. Measurement of intraocular lens (IOL) alignment implanted in patients in cataract surgery is important to(More)
PURPOSE Measurement of crystalline lens geometry in vivo is critical to optimize performance of state-of-the-art cataract surgery. We used custom-developed quantitative anterior segment optical coherence tomography (OCT) and developed dedicated algorithms to estimate lens volume (VOL), equatorial diameter (DIA), and equatorial plane position (EPP). (More)
In vivo three-dimensional (3-D) anterior segment biometry before and after cataract surgery was analyzed by using custom high-resolution high-speed anterior segment spectral domain Optical Coherence Tomography (OCT). The system was provided with custom algorithms for denoising, segmentation, full distortion correction (fan and optical) and merging of the(More)
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