Judith A. Walmsley

Learn More
[Au(en)Cl(2)]Cl.2H(2)O, where en = ethylenediamine (1,2-diaminoethane), has been synthesized, and its structure has been solved for the first time by the single-crystal X-ray diffraction method. The complex has square-planar geometry about Au(III), and the anionic Cl- is located in the apical position and at a distance of 3.3033(10) A compared to 2.2811(9)(More)
The interaction of guanine, guanosine or 50-GMP (guanosine 50-monophosphate) with [Pd(en)(H2O)2](NO3)2 and [Pd(dapol)(H2O)2](NO3)2, where en is ethylenediamine and dapol is 2-hydroxy-1,3-propanediamine, were studied by UV–Vis, pH titration and H NMR. The pH titration data show that both N1 and N7 can coordinate to [Pd(en)(H2O)2] 2þ or [Pd(dapol)(H2O)2] 2þ.(More)
The dimeric complex of dibromo(ethylenediamine)palladium(II) observed in water was investigated using electrospray mass spectrometry. One microM aqueous solutions of Pd(en)Br2 yielded a variety of previously unreported species. The most abundant ion observed was attributable to the Pd(en)Br2.Pd(en)Br+ dimeric complex at m/z 568.7 (most abundant stable(More)
Scanning electron microscopy images of the Na(+), K(+), and Rb(+) salts of guanosine 5'-monophosphate (5'-GMP) in the presence of the corresponding metal chloride have shown the formation of exceptionally large molecular aggregates. These are much larger than those previously reported in solution. Each cation system produced a solid with a different(More)
The tetrabutylammonium salt of guanosine 5'-monophosphate (5'-GMP) dissolves in DMSO-d6 forming aggregated species which exhibit some properties of reverse micelles. 1H NOESY experiments show that the 5'-GMP adopts the syn conformation about the glycosidic bond. Molecular mechanics calculations reveal a stable structure with this conformation in which the(More)
The (31)P NMR spectra of (TMA)(2)(5'-GMP), where TMA is [(CH(3))(4)N](+) and 5'-GMP is guanosine 5'-monophosphate, and K(2)(5'-GMP), containing various amounts of KCl or TMACl, have been obtained at 2 degrees C. Variable-temperature spectra have also been obtained for K(2)(5'-GMP). The TMA(+) ion serves to neutralize the charge on the dianionic 5'-GMP and(More)
Guanine mono-, oligo-, and polynucleotides, including the guanine-rich telomeric sequences found at the ends of chromosomes, have been shown to form self-associated species which contain cyclic tetramers of hydrogen-bonded guanines (G-tetrads). In this study the effect of the tetramethylammonium (TMA+), Na+, and K+ ions on the self-aggregation of(More)
Two palladium(II) complexes, [Pd(phen)(N identical withCCH(3))(2)][O(3)SCF(3)](2) (1) and [Pd(phen)(mu-OH)](2)[O(3)SCF(3)](2).2H(2)O (2) (where phen= 1,10-phenanthroline), have been crystallized following the reaction of Pd(phen)Cl(2) with silver triflate, Ag(O(3)SCF(3)), in acetonitrile and water, respectively. The structures of both complexes are based on(More)
The title compound, [PdCl2(C6H16N3)](C7H7SO3), consists of a Pd atom bonded to two N atoms of the 1,4,7-triazacyclononane (TACN) ligand and two chloride ions, which define a distorted square-planar geometry. The third N atom of the TACN ligand is protonated and hydrogen bonds to the ptoluenesulfonate anion. The Cl—Pd—Cl angle is larger than the N—Pd—N(More)