Judit Simon

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BACKGROUND Treatment options for depression include antidepressants, psychological therapy and a combination of the two. AIMS To develop cost-effective clinical guidelines. METHOD Systematic literature reviews were used to identify clinical, utility and cost data. A decision analysis was then conducted to compare the benefits and costs of(More)
BACKGROUND Depressive symptoms are a major cause of disability in bipolar disorder and there are few safe and effective treatments. The combination of lamotrigine plus quetiapine potentially offers improved outcomes for people with bipolar depression. We aimed to determine if combination therapy with quetiapine plus lamotrigine leads to greater improvement(More)
BACKGROUND The economic burden and health service use of eating disorders have received little attention, although such data are necessary to estimate the implications of any changes in clinical practice for patient care and health care resource requirements. This systematic review reports the current international evidence on the resource use and cost of(More)
BACKGROUND Depression is highly prevalent within individuals diagnosed with schizophrenia, and is associated with an increased risk of suicide. There are no current evidence based treatments for low mood within this group. The specific targeting of co-morbid conditions within complex mental health problems lends itself to the development of short-term(More)
Amartya Sen's 'capability' approach is one of the most important and influential theoretical contributions to the understanding of human welfare in the last forty years. Capabilities refer to the alternative combination of functionings that an individual has reason to value and is able to achieve, whether they chose to do so or not (Sen, 1993). The value of(More)
INTRODUCTION Patient non-adherence to treatment is a major problem across most chronic diseases. In COPD and asthma treatments it is a complex issue because people need to make behavioral and lifestyle changes while taking medications. Poor adherence results in increased rates of morbidity and mortality, more frequent hospitalizations, and ultimately higher(More)
Summarising more than twenty year's business marketing literature Reid and Plank (2000) have found organisational buying behaviour (OBB) as a most frequently researched area in our discipline. Referring to Scott and Webster (1991) they state that conceptual development has been paramount in the OBB field while empirical testing has not. Emphasising the(More)
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