Judit Benczik

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Boron biodistribution after intravenous infusion of 4-dihydroxyborylphenylalanine-fructose (BPA-F) complex was investigated in six dogs. Blood samples were evaluated during and following doses of 205 and 250 mg/kgbw BPA in a 30 min infusion, and 500 mg/kgbw in a 1h infusion. Samples from whole blood, urine, brain and other organs were analysed for boron(More)
PURPOSE To determine the correlation between sequential changes in the brain of dogs after irradiation, as detected by magnetic resonance imaging (MRI), with the eventual appearance of histological lesions. Histology was performed 77-115 weeks after irradiation. MATERIALS AND METHODS Groups of five beagle dogs were irradiated to the brain with single(More)
This investigation was designed to determine the relative biological effectiveness (RBE) of an epithermal neutron beam (FiR 1 beam) using the brains of dogs. The FiR 1 beam was developed for the treatment of patients with glioma using boron neutron capture therapy. Comparisons were made between the effects of whole-brain irradiation with epithermal neutrons(More)
Boron neutron capture therapy (BNCT) is an experimental type of radiotherapy, presently being used to treat glioblastoma and melanoma. To improve patient safety and to determine the radiobiological characteristics of the epithermal neutron beam of Finnish BNCT facility (FiR 1) dose-response studies were carried on the brain of dogs before starting the(More)
A specially designed radio frequency receiver coil was used in a low-field-strength (0.1 T) magnetic resonance imager to improve the image quality of the Beagle brain. The aim was to obtain better distinction of anatomic details with a better signal-to-noise ratio in shorter imaging time. The spin-echo (TR/TE = 1200/100; TR is the repetition time and TE is(More)
In the present work, our goal was to match high-resolution computed tomography (CT) scans with cross-sectional anatomical pictures of the turkey (Meleagris gallopavo). Two male BUT 6 (a commercial line) turkeys were used. CT scans with 1 mm slice thickness were performed. The images covered the trunk from the level of the 9th cervical vertebra to the end of(More)
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