Jude Constable

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A report of four cases of severe myelodysplastic syndromes (MDS) culminating in death in cadaver renal recipients is presented. All patients received predominantly antimetabolite immunosuppressive therapy. Abnormal cytogenetics were found in two cases. Survival was brief in all cases from the time of diagnosis. These cases add to the increasing number of(More)
We investigated the effects of dietary constituents on glomerular filtration (GFR) and albumin excretion rates (AERs) in a cross-sectional study in 39 young subjects with insulin-dependent diabetes. Dietary protein intake correlated significantly in patients with GFRs less than 150 mL/min per 1.73 m2 (r = 0.53, n = 23, P = 0.009), but not with AER. GFR also(More)
Primary malignant melanoma arising inform the ovary is rare, with only 30 cases described in the literature to date. The case reported here occurred in a 19-year-old woman and was rapidly progressive, resulting in death only 37 days following initial presentation. Management of this case is discussed in the context of the other reported cases. Surgery,(More)
The utility of a new glucose reflectance meter (the Reflolux; Boehringer Mannheim) and the accuracy of visually interpreted strips (Haemo-Glukotest 20-800R; Boehringer Mannheim) for the determination of blood glucose levels were assessed in a study of 50 insulin-dependent diabetics who regularly used the strips for home monitoring of their blood glucose(More)
Thirty-two episodes of severe infection in 23 patients were treated with parenteral ceftazidime: 96% of the infections were cured or improved. Of 15 chest infections in cystic fibrosis patients, 14 responded satisfactorily to treatment, including 9 cases where Pseudomonas aeruginosa and 7 cases where Staphylococcus aureus was a pathogen. All seven cases of(More)
BACKGROUND People with a mental illness experience a higher burden of smoking-related disease. Smoke-free policies in mental health facilities provide an opportunity to reduce smoking-related harms for patients and staff alike. Limited evidence regarding the effect of such policies on preventing smoking in mental health facilities has been reported. The(More)
BACKGROUND Frontal sinus mucocoeles require a structured approach to their surgical management. We share our experience of a novel method of positional classification for frontal mucocoele and corresponding surgical algorithm. METHODS A retrospective case-note review examined all frontal sinus surgery for mucocoele, spanning three years (2008-2010).(More)
Unlike some thiazide diuretics, indapamide--a non-thiazide chlorosulphonamide derivative--has been shown to have a magnesium-sparing effect in normotensive subjects. This effect has not been studied in hypertensive subjects. In a randomised double-blind trial indapamide 2,5 mg and placebo were given daily to a group of elderly patients with mild(More)
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