Juan-tian Liu

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Ghrelin is an endogenous ligand for the growth hormone secretagogue (GHS) receptor. Ghrelin is involved in feeding behaviour and is a potent stimulator of GH release. Chronically increased GH concentrations are known to negatively regulate the pituitary GHS receptor. This study tested whether chronic changes in peripheral GH levels/action affect ghrelin(More)
In this study we document the sensitivity of the leech pharynx to acetylcholine and begin to characterize the acetylcholine receptor mediating this response by examining the effects of selective cholinergic agonists and antagonists on the contractile behavior of the pharynx. The order of potency derived from the EC50 of each agonist was (+/-)epibatidine >(More)
Stimulated by PHA, the T cells responded well to exogenous IL-2, IL-4 or IL-6, but the responses were inhibited by FK-506 or cyclosporin A (Cs A). In contrast, when stimulated by PMA, the T cells responded to IL-2 and IL-4, but not to IL-6 and the responses were not inhibited by FK-506 and Cs A. Kinetic studies showed that FK-506 and Cs A had no inhibitory(More)
OBJECTIVE To observe the effects of quercetin on angiotensin (Ang II) induced interleukin-6 (IL-6) in vascular smooth muscle cells (VSMCs). METHODS VSMCs were isolated from the thoracic aorta of Sprague-Dawley rats and were stimulated with different doses of Ang II. The production of IL-6 in supernatant of quercetin treated cultures was detected by ELISA.(More)
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