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The effects of external anions (SCN−, NO 3 − , I−, Br−, F−, glutamate, and aspartate) on gating of Ca2+-dependent Cl− channels from rat parotid acinar cells were studied using the whole-cell configuration of the patch-clamp technique. Shifts in the reversal potential of the current induced by replacement of external Cl− with foreign anions, gave the(More)
BACKGROUND Mitoxantrone/prednisone ameliorates symptoms in hormone refractory prostate cancer (HRPC) but has no effect on survival. Docetaxel (Taxotere)/estramustine improves response but with significant toxicity. We reasoned that a sequential administration of the two regimens could be a viable alternative for delivering full doses of chemotherapy,(More)
Infantile regurgitation is a frequently occurring problem. Throughout the world, anxious parents are imploring physicians to eliminate their infant's regurgitation. General practitioners, pediatricians and pediatric gastroenterologists strive to alleviate infantile regurgitation and its related parental stress. In this paper we define the scope of the(More)
  • J A Santiago
  • 1993
Our experience with transurethral sphincterotomy in the spinal cord injured population of the Milwaukee VA Medical Center is reviewed. The 10-year retrospective analysis disclosed the operative procedure had to be repeated in nine out of 25 patients. The original success rate of the procedure was high, but significant failure appeared later. Possible(More)
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