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MicroRNA-200c regulates cisplatin resistance by targeting ZEB2 in human gastric cancer cells.
This study was specifically designed to confirm the hypothesis that microRNA-200c (miR-200c) affects the development of cisplatin (DDP) resistance in human gastric cancer cells by targeting zinc… Expand
Tumor necrosis factor-α induces ADAMTS-4 expression in human osteoarthritis chondrocytes.
Tumor necrosis factor (TNF)-α and a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4) are important in osteoarthritis (OA) cartilage degradation. In the present study, we… Expand
Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Enteropathogenic E. coli NleB and related type III effectors catalyze arginine GlcNAcylation of death domain (DD) proteins to block host defense, but the underlying mechanism is unknown. Here we… Expand
High prevalence of Neisseria gonorrhoeae with high-level resistance to azithromycin in Hangzhou, China.
- Chunshan Ni, Juan Xue, C. Zhang, H. Zhou, Stijn van der Veen
- Biology, Medicine
- The Journal of antimicrobial chemotherapy
- 1 August 2016
Department of Microbiology and Parasitology, School of Medicine, Zhejiang University, Hangzhou, China; Clinical Laboratory, Zhejiang Xiaoshan Hospital, Hangzhou, China; Urology Department, Zhejiang… Expand
Occurrence of high-level azithromycin-resistant Neisseria gonorrhoeae isolates in China.
Biomimetic Optical Cellulose Nanocrystal Films with Controllable Iridescent Color and Environmental Stimuli-Responsive Chromism.
- Yao-dong He, Ze-Lian Zhang, +5 authors Yu-Zhong Wang
- Materials Science, Medicine
- ACS applied materials & interfaces
- 2 February 2018
As a wise and profound teacher, nature provides numerous creatures with rich colors to us. To biomimic structural colors in nature as well as color changes responsive to environmental stimuli, there… Expand
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells
- L. Luo, Y. Liu, +4 authors F. Yang
- Saudi journal of gastroenterology : official…
- 1 September 2019
Background/Aims: This study was carried out to investigate the effect of Bletilla striata polysaccharide (BSP) treating on lipopolysaccharide (LPS)-induced intestinal epithelial barrier disruption in… Expand
Arginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium
Salmonella enterica serovar Typhimurium, an intracellular Gram-negative bacterial pathogen, employs two type III secretion systems to deliver virulence effector proteins to host cells. One such… Expand
Arginine-GlcNAcylation of death domain and NleB/SseK proteins is crucial for bacteria pathogenesis by regulating host cell death
Death receptor signaling is critical for cell death, inflammation, and immune homeostasis. Hijacking death receptors and their corresponding adaptors through type III secretion system (T3SS)… Expand
Simultaneous Determination of Four Triterpenoid Saponins in Aralia elata Leaves by HPLC-ELSD Combined with Hierarchical Clustering Analysis.
- Yichun Sun, Baimei Li, +6 authors Haixue Kuang
- Chemistry, Medicine
- Phytochemical analysis : PCA
- 1 May 2017
INTRODUCTION Aralia elata leaves are known to have several biological activities, including anti-arrythmia, antitumor, anti-inflammatory, anti-fatigue, antimicrobial and antiviral effects. Our… Expand