Juan-Xia Zhu

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To determine whether the effect of electroacupuncture (EA) on electroconvulsive shock (ECS) was through affecting endogenous opioid peptidergic system in the hippocampus, we used radioimmunoassay (RIA) to measure leu-enkephalin- and beta-endorphin-like immunoreactivity (L-E-LI and Beta-E-LI) in the hippocampal perfusate after ECS and EA treatments. Wistar(More)
Our previous studies have indicated that the thalamic nucleus submedius (Sm) is involved in modulation of nociception as part of an ascending component of an endogenous analgesic system consisting of spinal cord-Sm-ventrolateral orbital cortex (VLO)-periaqueductal gray (PAG)-spinal cord loop and that microinjection of 5-hydroxytryptamine (5-HT) into Sm(More)
The present study examined the role of α₂ adrenoceptor in mediating noradrenaline action in the ventrolateral orbital cortex (VLO) on allodynia induced by spared nerve injury (SNI) in the rat. The mechanical paw withdrawal threshold (PWT) was measured using von-Frey filaments. Microinjection of noradrenaline (1, 2, 4 μg in 0.5 μl) into the VLO,(More)
Our previous studies have indicated that the thalamic nucleus submedius (Sm) is involved in modulation of nociception as part of an ascending component of an endogenous analgesic system consisting of spinal cord-Sm-ventrolateral orbital cortex (VLO)-periaqueductal gray (PAG)-spinal cord loop. Microinjection of 5-hydroxytryptamine (5-HT) into Sm produces(More)
Previous studies have indicated that the thalamic nucleus submedius (Sm) and the anterior pretectal nucleus (APtN) are involved in the descending modulation of nociception. The aim of the present study was to examine whether the opioid receptors in the Sm and APtN mediated the electroacupuncture (EA)-produced analgesia. The latency of tail flick (TF) reflex(More)
Radioreceptor-binding assay combined with autoradiography technique in the brain slices of rats was used to investigate cerebral areas related to electroconvulsive shock (ECS) and to analyze changes of opioid receptors of these areas in electroacupuncture (EA) anticonvulsion. The results from image processing and detection of optic density (O.D.) showed(More)
RIA and HPLC-ECD were used respectively to detect beta-endorphin-like immunoreactive substances (beta-EPIS), noradrenaline and 3-methoxy-4-hydroxyphenyloglycol (MHPG), a noradrenaline metabolite, in the perfusate from the rabbit's preoptic area before and after 10 min of electroacupuncture (EA). It was found that, the content of beta-EPIS in the perfusate(More)
The present work studied the effect of preoptic catecholamine on acupuncture analgesia. The catecholaminergic terminals were destructed by microinjection of 6-hydroxydopamine into the preoptic area and the destruction was checked by fluorescence histochemical method. The results showed that the destruction of catecholaminergic terminals significantly(More)
  • S J Hu, J Zhu
  • 1989
Injection of a compound algogenic substance into receptive field of the skin induced sustained discharges of polymodal nociceptors in rats. The sustained discharges were obviously increased by stimulation of the sympathetic nerve innervating the receptive field. Initial facilitation was followed by the inhibition of discharges in partial units. The(More)