Juan Pablo Soto

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The insert of a clone from a lambdagt11 Echinococcus granulosus (Platyhelminth, Cestoda) protoscolex cDNA library, showed an open reading frame whose deduced protein sequence presents a high homology with all described thioredoxins (TRX). The TRX active site (Trp-Cys-Gly-Pro-Cys) is completely conserved. With a monospecific antibody, selected from a total(More)
Developing Knowledge Management Systems is a complicated task since it is necessary to take into account how the knowledge is generated, how it can be distributed in order to reuse it and other aspects related to the knowledge flows. On the other hand, many technical aspects should also be considered such as what knowledge representation or retrieval(More)
Adenosine triphosphate (ATP) is released by alveolar epithelial cells during ventilator-induced lung injury (VILI) and regulates fluid transport across epithelia. High CO(2) levels are observed in patients with "permissive hypercapnia," which inhibits alveolar fluid reabsorption (AFR) in alveolar epithelial cells. The authors set out to determine whether(More)
Developing knowledge management systems is a complicated task since it is necessary to take into account how the knowledge is generated, how it can be distributed in order to reuse it, and other aspects related to the knowledge flows. On the other hand, many technical aspects should also be considered such as what knowledge representation or retrieval(More)
UNLABELLED The viral capsid of HIV-1 interacts with a number of host factors to orchestrate uncoating and regulate downstream events, such as reverse transcription, nuclear entry, and integration site targeting. PF-3450074 (PF74), an HIV-1 capsid-targeting low-molecular-weight antiviral compound, directly binds to the capsid (CA) protein at a site also(More)