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BACKGROUND The relevance of TBX20 gene in heart development has been demonstrated in many animal models, but there are few works that try to elucidate the effect of TBX20 mutations in human congenital heart diseases. In these studies, all missense mutations associated with atrial septal defect (ASD) were found in the DNA-binding T-box domain, none in the(More)
BACKGROUND Percutaneous closure of patent ductus arteriosus has become the treatment of choice in many centres. In patients with large ducts and pulmonary hypertension, transcatheter closure has been achieved with success using the Amplatzer Duct Occluder or even the Amplatzer Muscular Ventricular Septal Defect Occluder. MATERIALS AND METHODS We present a(More)
INTRODUCTION Percutaneous closure of atrial septal defects is an alternative to surgical treatment. OBJECTIVES We report the results of percutaneous closure of atrial septal defects with the Amplatzer(®) device. METHOD We include patients taken to the catheterization laboratory from September 1997 to December 2011. RESULTS We proceeded with defect(More)
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