Juan-Pablo Horcajada

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OBJECTIVE To compare a mixing vs. a cycling strategy of use of anti-Pseudomonas antibiotics on the acquisition of resistant Gram-negative bacilli in the critical care setting. DESIGN Prospective, open, comparative study of two strategies of antibiotic use. SETTING Two medical intensive care units of a university hospital. PATIENTS A total of 346(More)
Based on an unselected material forty-seven cases of intraspinal neurinomas treated in a period of seven years, this report presents a comprehensive, clinical and statistical analysis. Divergences from the literature in respect of case history, distribution and frequency are pointed out. Attention is paid to the difficulties of early diagnosis. Problems of(More)
INTRODUCTION Despite many advances, the management of prosthetic joint infection is still a complex issue. Moreover, in recent years the problem of antimicrobial resistance has emerged as an important challenge. AREAS COVERED We analysed recent advances in different aspects of prosthetic joint infections. The importance of biofilms needs to be considered(More)
Introduction: A hallmark of sepsis is early onset microvascular dysfunction. However, the mechanism responsible for maldistribution of capillary blood flow is not understood. Evidence suggests red blood cells (RBC) can sense local oxygen (O2) conditions and signal the vasculature, via adenosine triphosphate (ATP), to increase capillary flow. We hypothesized(More)
Unfortunately, the original version of this supplement [1] contained errors in two of the abstracts; P037 and P127. Please see details below. In P037, the image presented as Figure eight is incorrect. The correct figure is shown below (Fig. 1). In P127, the author list presented is incorrect. The correct author list is as below. R Iqbal; Y Alhamdi; N(More)