Juan Manuel Serrano

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The pharmacokinetics of oxytetracycline were studied in goats, after the intravenous and intramuscular injection of a conventional and long-acting formulation. The antibiotic was distributed according to an open two-compartment model. The apparent volume of distribution (Vz) and the central compartment volume (Vc) were 1.443 litres/kg and 0.453 litre/kg,(More)
Our objective was to compare the ability to discriminate and categorize emotional facial expressions (EFEs) and facial identity characteristics (age and/or gender) in a group of 53 individuals with Parkinson's disease (PD) and another group of 53 healthy subjects. On the one hand, by means of discrimination and identification tasks, we compared two stages(More)
On the assumption that the ability to discriminate facial expressions has adaptive value to infants during early social exchanges, ethologically based theorists have argued that this ability is innate. Guided by this perspective, we investigated the ability of infants, 4-6 months old to recognize and discriminate facial expressions of anger, fear, and(More)
Although neutral faces do not initially convey an explicit emotional message, it has been found that individuals tend to assign them an affective content. Moreover, previous research has shown that affective judgments are mediated by the task they have to perform. Using functional magnetic resonance imaging in 21 healthy participants, we focus this study on(More)
The perception of and memory for faces, with or without emotional content, were studied in 43 patients with temporal lobe epilepsy who had undergone unilateral resection of the hippocampus and the amygdala and in 43 healthy participants for comparison. Each participant performed four tasks from the Florida Affect Battery (Facial Discrimination, Affect(More)
Aneurysm of the anterior mitral leaflet is a rare complication of infective aortic valve endocarditis, the natural evolution of which is generally its rupture, with subsequent acute and severe mitral regurgitation. Its presence cannot be recognized with transthoracic echocardiography and even in surgery. We describe a 78-year-old man with aortic valve(More)
The pharmacokinetics (PK) of moxifloxacin in healthy white New Zealand rabbits was studied following intravenous (IV) and subcutaneous (SC) administration routes as well as a SC long-acting poloxamer 407 gel formulation (SC-P407). Moxifloxacin concentrations were determined by high-performance liquid chromatography assay with fluorescence detection. Mean(More)