Juan Manuel Fernández

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Strontium ranelate (SR) is an orally administered and bone-targeting anti-osteoporotic agent that increases osteoblast-mediated bone formation while decreasing osteoclastic bone resorption, and thus reduces the risk of vertebral and femoral bone fractures in postmenopausal women with osteoporosis. Osteoblastic alkaline phosphatase (ALP) is a key enzyme(More)
Assistive technologies need to constantly adapt and react to user needs. To this end, ambient intelligence techniques could be adopted. One approach consists of defining suitable rules to trigger actions or suggestions to the users. In this paper, ATML (Ambient intelligence Trigger Markup Language), a novel suitable language, is presented and described.(More)
People going back to home after a discharge needs to come back to their normal life. Unfortunately, it becomes very difficult for people with severe disabilities, such as a traumatic brain injury. Thus, this kind of users needs, from the one hand, a telemonitoring system that allows therapists and caregivers to be aware about their status and, from the(More)
Divergent concepts on the origin of the dicrotic notch are widespread in medical literature and education. Since most medical textbooks explain the origin of the dicrotic notch as caused by the aortic valve closure itself, this is commonly transmitted in medical physiology courses. We present clinical data and numerical simulations to demonstrate that(More)
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